Stem Cell Core

Overview of Services

The Mission of the Stem Cell Core is to provide research grade induced pluripotent stem cells (iPSCs) and other relevant iPSC-derived cell types to investigators, and to facilitate the generation of clinical quality cells for cell therapy.

iPSC technology is on the cutting edge of modern medical science, generating individualized stem cell therapies from mature cells, such as skin, to provide patient specific progenitor cells for directed repair of damaged tissues. iPSCs can differentiate to all cell types in the body including cardiomyocytes for heart damage, hepatocytes for liver damage, keratinocytes for skin repair, dopaminergic neurons for Parkinson’s disease, alveolar type II cells for respiratory patients, and pancreatic insulin producing islet cells for diabetics. Moreover, iPSC technology has also applied in repairing genetic diseases by correcting the DNA sequences in the patient-specific-derived  iPSC and differentiating the now healthy iPS cells to the desired cells, to be used to replace the abnormal cells. Additionally, iPSC technology is an ideal in vitro model to study disease pathogenesis and drug screening.

 
Schematic representation of iPSC reprograming.

 

Leadership

Garnett Mingledorff
Lab Specialist

gam7t@virginia.edu 

Location and hours of operation

Hours Location

Monday - Friday

8:30 am - 12 pm

1 pm - 5 pm  

 Pinn Hall 1071

Links and Resources

Contacts

Name Role Phone Email Location
Garnett Mingledorff
Lab Specialist
 
434-924-1753
 
gam7t@virginia.edu
 
Pinn Hall 1066
 

Price list


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